Michele Kliem

Michele A. Kliem, Ph.D.

Patent Agent

Michele A. Kliem is an experienced patent agent and a member of the biotechnology and pharmaceutical practice teams in Ballard Spahr's Patents Group. Michele drafts and prosecutes patent applications in the biological and pharmaceutical arts, including immunology, biotechnology, drug delivery systems, life sciences, pharmaceuticals, neuroscience, drug formulations, genetics, molecular biology and medical devices. She also prepares infringement and validity analyses, and assists with litigation, pre-litigation strategic planning, and the filing of Abbreviated New Drug Applications and notice letters.

Michele's previous research encompasses the neuronal recording of brain electrical circuits, intracerebral drug injections, spinal cord viral vector injections, microdialysis, electron microscopy, immunocytochemistry, immunohistochemistry, and immunofluorescence.

Professional Highlights

Professional Activities

Society for Neuroscience

International Basal Ganglia Society

Instructor, Georgia Institute of Technology, Department of Applied Physiology, 2010-present


Michele has co-authored numerous scientific publications, including:

"Addressing Breach of Method-of-Use Patents by Generics," Law360, May 2, 2012

"Assessment of Hippocampal Adena-associated Viral Vector Gene Delivery via Frarneless Stereotaxis in a Nonhuman Primate," Stereotactic Functional Neurosurgery, 89(5):275-85, 2011

"Intramuscular Administration of a VEGF Zinc Finger Transcription Factor Activator (VEGF-ZFP-TF) Improves Functional Outcomes in SOD1 Rats," Amyotrophic Lateral Sclerosis, 12(5):331-9, 2011



Emory University (Ph.D. 2008, pharmacology)

University of Toledo (M.S. 1994, pharmacology)

Ashland University (B.S. 1992, biology)
Honors Program; Recipient, Presidential Scholarship, Ohio Choice Grant, and H. Gehman Chemistry Scholarship


U.S. Patent and Trademark Office